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Hypoalbuminemia results from decreased production, seen with severe hepatic insufficiency, or by loss through increased rates of urinary excretion, such as in nephrotic syndrome or with mucosal damage, as with protein losing enteropathies

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Their mean plasma ammonia concentration was within the normal range, but 24 patients (35.3%) with ammonia concentrations above 80 g/dl were considered hyperammonaemic and 15 of these 24 (22.1%) had ammonia concentrations above 100 g/dl